Омилија на 1 Јн 2, 12–17

Dmd063479 1208..1217

We developed murine Cyp3a knockout (KO) chimeric mice with humanized liver expressing human P450s similar to those in humans and whose livers and small intestines do not express murine Cyp3a. This approach may overcome effects of residual mouse metabolic enzymes like Cyp3a in conventional chimeric mice with humanized liver, such as PXB-mice [urokinase plasminogen activator/severe combined immun...

A Prospective Study of 1217 Patients

1212-1217 Murtaza LAJP 3371:Murtaza

Preparation and in vitro characterization of floating microparticles loaded with cimetidine (FMC) for oral delivery was the objective of this study. Non-solvent addition coacervation technique using hydroxypropylmethylcellulose (HPMC) as the rate controlling polymer was employed to achieve FMC. Three formulations of FMC were prepared and optimized regarding encapsulation efficiency and dissolut...

Cover Vol.1, No.2

LAPTH - 1217/07 An evolutionary model with Turing machines

The development of a large non-coding fraction in eukaryotic DNA and the phenomenon of the code-bloat in the field of evolutionary computations show a striking similarity. This seems to suggest that (in the presence of mechanisms of code growth) the evolution of a complex code can’t be attained without maintaining a large inactive fraction. To test this hypothesis we performed computer simulati...